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From Genes to Hearing: What Otolaryngologists Need to Know About Gene Therapy for Hearing Loss

by Eliot Shearer, MD, PhD, and Samantha Anne, MD, MS • September 3, 2026

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Dr. Shearer

Dr. Shearer is a pediatric otolaryngologist at Boston Children’s Hospital, where he leads the Translational Hearing Genomics Lab. He is currently running a clinical trial for ultra-rapid genomic newborn hearing screening. Dr. Shearer has expertise in clinical trials for gene therapy and is the site principal investigator for two sponsored clinical trials for gene therapy for hearing loss.  Disclosures: Dr. Shearer is the clinical trial site principal investigator and scientific advisor for Eli Lilly and Regeneron. He receives funding from the National Institutes of Health, Boston Children’s Translational Research Program, and Eli Lilly as well as philanthropy.

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Explore This Issue
September 2026

Dr. Anne

Dr. Anne is a professor of otolaryngology-head and neck surgery and the medical director for pediatric ear and hearing disorders at the Head and Neck Institute at Cleveland Clinic in Cleveland, Ohio. Disclosures: Dr. Anne is a consultant for Eli Lilly and Regeneron and receives royalties from Plural Publishing.

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Filed Under: ENT Perspectives, Home Slider, Viewpoint Issue: September 2026

You Might Also Like:

  • Excitement Around Gene Therapy for Hearing Restoration
  • Genetic Testing for Hearing Loss
  • Innovations in Otolaryngology: Two Paths to Progress
  • Gene Therapy: A Promising Role in Otolaryngology

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