Out of 287 patients with severe dysplasia and cancer in situ, the control rate was 85%, with a follow-up after at least 30 months.
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For 185 patients with T1a lesions, the control rate was 91%. For 14 patients with T1b and T2 lesions, the rate was 82%. For 31 patients with recurrent T1 lesions who received post-op radiation therapy, it was 79%, and for 27 patients with either verrucous and spindle-cell carcinoma, it was 90%.
In a 2007 study by Michael Hinni, MD, et al., 117 patients were treated with transoral laser miscrosurgery for lesions from T2 to T4, both glottic and supraglottic, with 45 also receiving radiation therapy. For 92% of the patients, the larynx remained intact. The five-year local control rate was 74%, and the combined local and regional rate was 68%.
©2009 The Triological Society