Synopsis: One-year follow up of three cohorts showed significantly better improvement in multiple disease-specific QOL measures in the surgical patients (n = 65) and medically managed patients who crossed over to the surgical arm during the study (n=17) than in medically managed patients (n = 33). Patients who were initially treated medically and switched to the surgical arm did so due to persistence or worsening of disease. This prospective study reports that, at a one-year follow-up, patients electing surgery for CRS showed greater improvement than patients electing medical therapy alone.
Bottom line: In patients who are candidates for ESS, the surgery results in greater disease-specific QOL improvements than medical therapy.
Citation: Smith TL, Kern R, Palmer JN, et al. Medical therapy vs surgery for chronic rhinosinusitis: a prospective, multi-institutional study with 1-year follow-up. Int Forum Allergy Rhinol. 2012;3:4-9.