Are measurements of real-world clinical outcomes other than the apnea-hypopnea index (AHI) useful in managing obstructive sleep apnea (OSA)?
Background: The gold standard assessment for OSA is polysomnography (PSG). During PSG, the frequency of obstructive events is reported as the AHI, and surgical treatment effectiveness for OSA is almost exclusively based on reported AHI changes; however, there is a disconnect between the levels of AHI used to denote outcomes of therapy and real-world clinical outcomes such as quality of life (QOL), patient perception of disease, cardiovascular measures, or survival.
Explore this issue:January 2014
Study design: Systematic review of 21 cohort and review studies from 1997 to 2012.
Setting: PubMed database.