ENTtoday
  • Home
  • COVID-19
  • Practice Focus
    • Allergy
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Departments
    • Issue Archive
    • TRIO Best Practices
      • Allergy
      • Facial Plastic/Reconstructive
      • Head and Neck
      • Laryngology
      • Otology/Neurotology
      • Pediatric
      • Rhinology
      • Sleep Medicine
    • Career Development
    • Case of the Month
    • Everyday Ethics
    • Health Policy
    • Legal Matters
    • Letter From the Editor
    • Medical Education
    • Online Exclusives
    • Practice Management
    • Resident Focus
    • Rx: Wellness
    • Special Reports
    • Tech Talk
    • Viewpoint
    • What’s Your O.R. Playlist?
  • Literature Reviews
    • Allergy
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Events
    • Featured Events
    • TRIO Meetings
  • Contact Us
    • About Us
    • Editorial Board
    • Triological Society
    • Advertising Staff
    • Subscribe
  • Advertise
    • Place an Ad
    • Classifieds
    • Rate Card
  • Search

Transoral Laser Resection for Early Glottic Cancer

by Jennifer Decker Arevalo, MA • March 1, 2008

  • Tweet
  • Email
Print-Friendly Version

During her presentation at the 2007 Combined Otolaryngology Spring Meeting in San Diego, Dana M. Hartl, MD, PhD, from the Department of Otolaryngology Head and Neck Surgery at the Institut Gustave Roussy in France, described her findings from a retrospective, bi-institutional study designed to review the results of a large series of patients with early glottic squamous cell carcinoma treated with curative intent by transoral laser resection.

You Might Also Like

  • Laser Treatment Resolves Glottic Cancer in a Pilot Study
  • Laser, Radiotherapy Appear Similar in Oncologic Outcomes for Glottic Cancer
  • Cost Analysis of Transoral Surgery versus XRT for Early-Stage Glottic Cancer
  • Extent of ELS Resections Determines Vocal Quality Following Transoral Laser Microsurgery
Explore This Issue
March 2008

We also sought to compare these results with the pathological assessment of the resection margins, involvement of the anterior commissure, and the extent of the cordectomy, said Dr. Hartl, whose study was published in the Annals of Otology, Rhinology, and Laryngology.

Since the 1990s, transoral laser resection has become a standard treatment for early glottic cancer and a valid alternative to radiation therapy or external partial laryngectomy in terms of oncologic results. Studies have shown that transoral laser resection provides greater than 90% local control and laryngeal preservation for early glottic cancer.

According to Dr. Hartl, the use of this technique requires specific equipment and instrumentation, adequate exposure of the larynx, and specific surgical training and experience. Pathologists analyzing surgical specimens after laser resection also require training and experience because of the small resection specimens and the peripheral coagulation effect (0.5 mm) of laser on resection margins.

Details of the Study

Of 142 patients, 79 were selected for this study, based on their pT stage, the availability of information regarding resection margins, the absence of adjuvant radiation therapy, and evidence of follow-up for at least two years.

Tumors were classified pTis (n = 21), pT1a (n = 51), or pT1b (n = 7) and were treated by cordectomy types I (23%), II (30%), III (27%), IV (6%), and V (14%), based on the European Laryngological Society’s classifications of endoscopic laser cordectomies. Type I is a subepithelial resection (respecting the vocal ligament). Type II is a subligamental resection. Type III is intramuscular (partial resection of the vocalis muscle). Type IV is a total resection of the vocal fold. Type V is an extended cordectomy with subtypes indicating extension to include the anterior commissure (type Va), the arytenoid cartilage (type Vb), the false vocal fold (type Vc), or the subglottis (type Vd).

Surgeons performed the cordectomies with en bloc resection; pathologists considered the resection margins to be: free (tumor at least 2 mm from the edge of the specimen), positive (tumor at the margin of the specimen), or suspicious (tumor less than 2 mm from the edge of the specimen).

Dana M. Hartl, MD, PhD

Dana M. Hartl, MD, PhD

The average follow-up was 56 months. The overall five-year actuarial recurrence-free survival rate was 89%, and the five-year actuarial disease-specific survival rate was 97.3%. Eleven local recurrences occurred; seven were treated by another laser resection, one by radiation therapy, one by supracricoid partial laryngectomy, and two by total laryngectomy.

Pages: 1 2 3 | Single Page

Filed Under: Departments, Laryngology, Medical Education, Practice Focus, Tech Talk Tagged With: cancer, carcinoma, CT, laser, outcomes, research, surgery, technology, treatment, tumorIssue: March 2008

You Might Also Like:

  • Laser Treatment Resolves Glottic Cancer in a Pilot Study
  • Laser, Radiotherapy Appear Similar in Oncologic Outcomes for Glottic Cancer
  • Cost Analysis of Transoral Surgery versus XRT for Early-Stage Glottic Cancer
  • Extent of ELS Resections Determines Vocal Quality Following Transoral Laser Microsurgery

The Triological SocietyENTtoday is a publication of The Triological Society.

The Laryngoscope
Ensure you have all the latest research at your fingertips; Subscribe to The Laryngoscope today!

Laryngoscope Investigative Otolaryngology
Open access journal in otolaryngology – head and neck surgery is currently accepting submissions.

Classifieds

View the classified ads »

TRIO Best Practices

View the TRIO Best Practices »

Top Articles for Residents

  • Do Training Programs Give Otolaryngology Residents the Necessary Tools to Do Productive Research?
  • Why More MDs, Medical Residents Are Choosing to Pursue Additional Academic Degrees
  • What Physicians Need to Know about Investing Before Hiring a Financial Advisor
  • Tips to Help You Regain Your Sense of Self
  • Should USMLE Step 1 Change from Numeric Score to Pass/Fail?
  • Popular this Week
  • Most Popular
  • Most Recent
    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment
    • Vertigo in the Elderly: What Does It Mean?
    • Experts Delve into Treatment Options for Laryngopharyngeal Reflux
    • Non-Acidic Reflux Explains Lack of Response to H2 Blockers and PPIs
    • How 3D Printing Is Transforming the Pediatric Otolaryngology Field
    • Vertigo in the Elderly: What Does It Mean?
    • New Developments in the Management of Eustachian Tube Dysfunction
    • Some Laryngopharyngeal Reflux Resists PPI Treatment
    • Eustachian Tuboplasty: A Potential New Option for Chronic Tube Dysfunction and Patulous Disease
    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment
    • Why Virtual Grand Rounds May Be Here to Stay
    • Otolaryngologist Leverages His Love of Pinball into Second Business
    • These New Imaging Advances May Help to Protect Parathyroids
    • Is the Training and Cost of a Fellowship Worth It? Here’s What Otolaryngologists Say
    • Which Otologic Procedures Poses the Greatest Risk of Aerosol Generation?

Polls

Have you used 3D-printed materials in your otolaryngology practice?

View Results

Loading ... Loading ...
  • Polls Archive
  • Home
  • Contact Us
  • Advertise
  • Privacy Policy
  • Terms of Use

Visit: The Triological Society • The Laryngoscope • Laryngoscope Investigative Otolaryngology

Wiley
© 2021 The Triological Society. All Rights Reserved.
ISSN 1559-4939

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.