Does commercially available alkaline drinking water reduce pepsin activity? Background: Pepsin, a key enzyme in the pathogenesis of both laryngopharyngeal and esophageal reflux disease, requires acid for its activation. Excessive acid in American diets may increase reflux disease, because pepsin is activated by a low pH (<4.6), which is found in all bottled and canned […]
Articles tagged with "reflux disease"
What are the areas of agreement and controversy in clinical practice guidelines for reflux disease, and is it feasible to create a clinical protocol for otolaryngologists? Background: With the movement in health care toward evidence-based medicine, is it important to identify best practice guidelines for reflux disease, including gastroesophageal reflux disease (GERD) and laryngopharyngeal reflux (LPR)? […]
PHOENIX-Eosinophilic esophagitis is a serious, growing problem that is little understood by many otolaryngologists, according to panelists discussing the disease. Some doctors who specialize in swallowing disorders acknowledged that they were not even aware of the problem, let alone well versed in diagnosing and treating the illness, according to results of a survey completed by 80 members of the American Broncho-Esophagological Association (ABEA).