How do the type of surgical procedure, volume of biopsy, tumor size, and location in the nasal fossa influence the reliability of pretreatment biopsies on nasoethmoidal tumors?
The risk of nasoethmoidal tumor misdiagnosis may be high even in referral centers. Obtaining abundant material under general anesthesia may reduce the risk of diagnostic error and inadequate treatment.
Explore this issue:August 2018
Background: Nasoethmoidal malignancies are rare diseases characterized by large histological variability. Pretreatment biopsy is crucial in histology-based management of malignant nasoethmoidal tumors because misdiagnosis can lead to inadequate therapeutic planning. The rarity of the disease and the wide range of histological variants explain the high rate of histologic discrepancies detected in sinonasal tumors after detailed revision by expert pathologists.
Study design: Retrospective case series of 77 patients from 252 cases, recorded from January 1995 to June 2016.