How does reflux affect laryngeal tissue quality?
Explore this issue:March 2011
Background: Laryngopharyngeal reflux has deleterious effects on the larynx. Due to the poor intrinsic protective mechanisms in this tissue, damage occurs at a higher pH and leads to the commonly known throat symptoms. The authors in this study have used endogenous acid and pepsin to study the mucosal changes in an animal model.
Study design: Randomized trial.