NEW ORLEANS—Otolaryngology’s ever-advancing frontier was on display here at the Triological Society Combined Sections Meeting in a session on new developments in pediatric otology, hearing loss in adults, Eustachian tube treatment, and nerve monitoring during bilateral thyroidectomy.
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March 2017Drug Delivery with Nanogel
Daniel Choo, MD, director of pediatric otolaryngology-head and neck surgery at Cincinnati Children’s Hospital Medical Center in Ohio, said using nanogel could be a better way to deliver therapies to the inner ear. In cases of childhood hearing loss caused by a cytomegalovirus (CMV) infection, prompt antiviral treatment can stabilize hearing or improve it, but more than 60% of children taking ganciclovir have to stop taking it or cut back on the dose because of Grade 3 or 4 neutropenia.
Standard application to the inner ear gives a quick peak in activity and doesn’t give the sustained response that’s needed, Dr. Choo said.