Probe-Based Confocal Laser Endomicroscopy Effective in Detecting Head and Neck Cancers

How feasible is the use of probe-based confocal laser endomicroscopy (pCLE) in standard practice for detecting head and neck cancers?

Background: pCLE is an emerging optical imaging technology that is rapidly being adopted for its ability to provide real-time, in-situ, histological visualization of tissue in the operating room. In 2013, oral cavity, pharyngeal, and laryngeal cancers accounted for a combined 53,640 new cancer cases in the United States alone. Despite modern advances in diagnosis and treatment, prognosis remains poor.

Study design: Six nondysplasia, seven dysplasia, and 11 squamous cell carcinoma (SCCA) cases reviewed at a single tertiary referral center.

Setting: Feist-Weiller Cancer Center, Louisiana State University Health Shreveport, Shreveport.

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