Study Raises Questions about Angioedema Management

What are the criteria for airway intervention in patients with angioedema?

Background: Angioedema is painless edema of the mucosal and cutaneous surfaces. The more common type is hereditary and is caused by defects in C1 esterase inhibitor, accumulation of bradykinin and mast cell degranulation. The goals were to determine trends in presentation, management and factors associated with the need for admission and airway intervention.

Study design: Retrospective chart review, describing the inciting factors, presentation, and clinical course of patients. A bivariate analysis using a Fisher’s exact test was performed.

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