What are the long-term results of preventing xerostomia through autotransplantation of the human submandibular gland?
Background: Intensity-modulated radiotherapy (RT) plays an important role in head and neck squamous cell carcinoma treatment. Generally, patients have a variety of subjective complaints because the parotid glands are spared only to some extent. One of the major side effects is xerostomia, which induces dysphagia, recurrent oral infections, and dysgeusia. Using autotransplantation, the irradiation dosage involving the submandibular gland can be partially reduced.
Explore this issue:July 2016
Study design: Follow-up on 11 patients enrolled in the study from November 2011 to May 2014.
Setting: University Hospital Wuerzburg, Germany.