Resectable stage IVA/IVB tumors should be treated with surgery followed by chemoradiation, with consideration for dabrafenib/trametinib biotherapy for BRAFV600E-mutated tumors.

Resectable stage IVA/IVB tumors should be treated with surgery followed by chemoradiation, with consideration for dabrafenib/trametinib biotherapy for BRAFV600E-mutated tumors.