Current literature suggests that topical TXA could potentially be a useful adjunct in the management of anterior epistaxis.

Is Topical Tranexamic Acid Effective in Treating Epistaxis?
Epistaxis is a common emergency department (ED) presentation. Many cases are self-limited, but other cases may require an intervention to stop bleeding. Methods to manage epistaxis include nasal compression, topical vasoconstrictors, cautery, nasal packing, and even surgical ligation in severe cases.