Although steroids are effective for many patients with autoimmune inner ear disease (AIED), there are still challenges in diagnosing the condition, mysteries behind what happens to the inner ear, and controversy over whether intratympanic injections help.
Explore this issue:December 2007
AIED is a rapidly-progressive bilateral sensorineural hearing loss. Usually, hearing loss occurs in one ear first, then progresses to the second ear. It is often not caught until there is a decline in hearing in the second ear. The condition tends to be steroid-responsive, but there are some controversies and uncertainties in their use for some types of AIED.
ENToday spoke to two thought leaders in the field: Jeffrey Harris, MD, PhD, Professor and Chief of Otolaryngology at the University of California, San Diego, and Steven Rauch, MD, Associate Professor of Otology and Laryngology at Harvard Medical School. Both agreed that, generally, steroids are effective for AIED, but because of side effects with long-term use there is a limit to their use. Steroids have a number of actions believed to help AIED and its various causes. They have anti-inflammatory action, are immunosuppressive, and can target glucocortcicoid receptors in the inner ear.| | | Next → | Single Page