What is the change in cardinal symptoms of chronic rhinosinusitis (CRS) for those undergoing medical therapy versus surgery for management?
Background: CRS is an inflammatory disorder of the paranasal sinuses defined symptomatically as 12 weeks or more of two or more “cardinal symptoms,” including nasal obstruction, thick nasal discharge, facial pain/pressure, and reduction or loss of sense of smell. While numerous studies have described the impact of surgery on these symptoms, this study seeks to compare the impact of surgery with that of ongoing medical therapy alone.
Explore this issue:May 2015
Study design: Prospective cohort.
Setting: Academic tertiary facilities, including University of California, San Diego; Oregon Health and Science University in Portland; University of Utah in Salt Lake City; and the Medical University of South Carolina in Charleston.