This review seeks to evaluate the best available evidence, focusing on the change in objective olfactory outcomes in CRSwNP after surgical intervention.
CRSwNP might be the most surgically responsive group in CRS in that current evidence supports short-term olfactory improvement after ESS in the treatment of CRSwNP. However, there is a lack of consensus on the extent of surgical intervention required to achieve improvement in olfaction. Also, variability in perioperative medical therapy, patient compliance, and severity of preoperative disease are factors that meaningfully impact the treatment outcome and are poorly adjusted for in the literature. When considering ESS, patients may be counseled regarding the unpredictable olfaction outcome after surgery, especially for the long-term, due to confounding factors such as medical treatments and variable disease severity.
In order to reach solid conclusions on the role of ESS on olfaction, the literature needs high-level and well-powered studies comparing olfaction outcomes of medical and surgical interventions separately, with consistent olfaction measures and long-term follow-up. We also suggest having a clear classification system of the extent of surgical intervention that is correlated with preoperative condition to better identify the surgery with the best olfaction outcomes (Laryngoscope. 2017;127: 2203–2204). | ← Previous | | | Next → | Single Page