What is the relative risk of having eosinophilic esophagitis (EoE) coexist with chronic rhinosinusitis (CRS) in probands and their families?
Background: EoE is a disease process that is defined by its eosinophilia and inflammatory changes. CRS is also an inflammatory disease, and eosinophilia has been shown to play one possible role in the development of certain subsets. EoE and CRS may share a common etiopathogenesis due to uncontrolled inflammation in their development. It is not known whether or not EoE and CRS share a familial link and are found to be prevalent as comorbid conditions.
Explore this issue:June 2016
Study design: Retrospective observational cohort study of CRS and EoE patients diagnosed at any age between 2008 and 2012 with population-based matched controls.
Setting: Utah Population Database, a genealogical database linked to medical records.