ENTtoday
  • Home
  • COVID-19
  • Practice Focus
    • Allergy
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Departments
    • Issue Archive
    • TRIO Best Practices
      • Allergy
      • Facial Plastic/Reconstructive
      • Head and Neck
      • Laryngology
      • Otology/Neurotology
      • Pediatric
      • Rhinology
      • Sleep Medicine
    • Career Development
    • Case of the Month
    • Everyday Ethics
    • Health Policy
    • Legal Matters
    • Letter From the Editor
    • Medical Education
    • Online Exclusives
    • Practice Management
    • Resident Focus
    • Rx: Wellness
    • Special Reports
    • Tech Talk
    • Viewpoint
    • What’s Your O.R. Playlist?
  • Literature Reviews
    • Allergy
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Events
    • Featured Events
    • TRIO Meetings
  • Contact Us
    • About Us
    • Editorial Board
    • Triological Society
    • Advertising Staff
    • Subscribe
  • Advertise
    • Place an Ad
    • Classifieds
    • Rate Card
  • Search

ITSI Effective for Some Cases of Idiopathic Tinnitus

by Amy Eckner • November 1, 2013

  • Tweet
  • Email
Print-Friendly Version

How effective is intratympanic steroid injection (ITSI) in treating idiopathic tinnitus?

Background: Subjective tinnitus is a conscious perception of a phantom sound that is audible only by the patient. The pathophysiology is still obscure. ITSI has been used frequently to treat various inner ear diseases, as well as idiopathic tinnitus; however, previous studies have not proven its effectiveness.

You Might Also Like

  • Neural Connectivity Changes Do Not Affect Bothersome Tinnitus Symptoms
  • 10 Minutes Supine Is Sufficient for Intratympanic Dexamethasone Injection
  • Cochlear Implantation Has Varying Effect on Tinnitus
  • IT Steroid Treatment, Oral Corticosteroid Therapy Similar for Sudden Sensorineural Hearing Loss
Explore This Issue
November 2013

Study design: A prospective, placebo-controlled, randomized, double-blind study of 30 patients with refractory tinnitus, treated between 2006 and 2007.

Setting: Department of Otolaryngology, Ajou University Hospital, Suwon, Republic of Korea.

Synopsis: Enrolled patients were randomly assigned to receive 0.3 ml to 0.4 ml intratympanic injections of either dexamethasone solution or isotonic sodium chloride solution. Intratympanic injections were performed twice a week for two weeks. ITSI efficacy was determined by comparing a tinnitus questionnaire, tinnitus handicaps index (THI) and tinnitus loudness scale at baseline and at four weeks after the last injection. Thirty patients (15 steroid, 15 saline) with refractory tinnitus completed the therapy, audiometry, tinnitogram, tinnitus questionnaire and THI. There were no differences between the steroid and the saline groups. Overall, ITSI treatment on refractory tinnitus appeared to be slightly more effective than saline injection, but there was no statistical difference between the steroid and saline groups. Side effects such as hearing loss, dizziness or eardrum perforation, or a hearing level change were not found in any patients during therapy and follow-up. Effective results, which were shown for patients with low-frequency compared with high-frequency tinnitus, had no statistical significance.

Bottom line: ITSI may not be effective for refractory tinnitus, so ITSI indication for tinnitus should be limited to specific cases.

Citation: Choi SJ, Lee JB, Lim JH, et al. Intratympanic dexamethasone injection for refractory tinnitus: prospective placebo-

controlled study. Laryngoscope. 2013;123:2817-2822.

—Reviewed by Amy Eckner

Filed Under: Literature Reviews, Otology/Neurotology, Otology/Neurotology Tagged With: idiopathic tinnitus, ITSI, steroid injectionIssue: November 2013

You Might Also Like:

  • Neural Connectivity Changes Do Not Affect Bothersome Tinnitus Symptoms
  • 10 Minutes Supine Is Sufficient for Intratympanic Dexamethasone Injection
  • Cochlear Implantation Has Varying Effect on Tinnitus
  • IT Steroid Treatment, Oral Corticosteroid Therapy Similar for Sudden Sensorineural Hearing Loss

The Triological SocietyENTtoday is a publication of The Triological Society.

The Laryngoscope
Ensure you have all the latest research at your fingertips; Subscribe to The Laryngoscope today!

Laryngoscope Investigative Otolaryngology
Open access journal in otolaryngology – head and neck surgery is currently accepting submissions.

Classifieds

View the classified ads »

TRIO Best Practices

View the TRIO Best Practices »

Top Articles for Residents

  • Do Training Programs Give Otolaryngology Residents the Necessary Tools to Do Productive Research?
  • Why More MDs, Medical Residents Are Choosing to Pursue Additional Academic Degrees
  • What Physicians Need to Know about Investing Before Hiring a Financial Advisor
  • Tips to Help You Regain Your Sense of Self
  • Should USMLE Step 1 Change from Numeric Score to Pass/Fail?
  • Popular this Week
  • Most Popular
  • Most Recent
    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment
    • Experts Delve into Treatment Options for Laryngopharyngeal Reflux
    • Vertigo in the Elderly: What Does It Mean?
    • A Look at the Latest Research on Subglottic Stenosis
    • Weaning Patients Off of PPIs
    • Vertigo in the Elderly: What Does It Mean?
    • New Developments in the Management of Eustachian Tube Dysfunction
    • Some Laryngopharyngeal Reflux Resists PPI Treatment
    • Eustachian Tuboplasty: A Potential New Option for Chronic Tube Dysfunction and Patulous Disease
    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment
    • COVID-19 Impacts on Physician Contracts
    • Do Perioperative Systemic Corticosteroids Improve Cochlear Implant Hearing Preservation?
    • Is Betahistine Effective in the Treatment of Ménière’s Disease?
    • What Is the Role of Radiofrequency Ablation for Benign Thyroid Nodules?
    • Is Preoperative Computed Tomography Necessary for Primary Stapes Surgery?

Polls

Do you ever talk about politics with your patients during appointments?

View Results

Loading ... Loading ...
  • Polls Archive
  • Home
  • Contact Us
  • Advertise
  • Privacy Policy
  • Terms of Use

Visit: The Triological Society • The Laryngoscope • Laryngoscope Investigative Otolaryngology

Wiley
© 2021 The Triological Society. All Rights Reserved.
ISSN 1559-4939

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.