What are the risks of post-tonsillectomy hemorrhage associated with peri-operative ketorolac use for adult and pediatric patients?
Background: Ketorolac, a nonsteroidal anti-inflammatory drug for analgesia, is associated with increased risk of post-operative hemorrhage in some settings; however, recommendations for its use lack clarity. A recent 2010 Cochrane review of NSAID use in children undergoing tonsillectomy found no statistically significant increased post-tonsillectomy hemorrhage risk in patients who receive ketorolac, while the 2011 American Academy of Otolaryngology–Head and Neck Surgery pediatric tonsillectomy guidelines advise avoiding ketorolac.
Explore this issue:August 2014
Study design: Systematic review and meta-analysis of 10 retrospective and prospective primary articles from 1970 to 2013.
Setting: PubMed database.| | | Next → | Single Page