What role does modified uvulopalatopharyngoplasty (UPPP), including tonsillectomy, play in the daytime sleepiness and quality of life (QOL) in patients with obstructive sleep apnea syndrome (OSAS)?
Background: OSAS is associated with increased morbidity and mortality, as well as increased risk of poor sleep and low QOL, excessive daytime sleepiness, and traffic accidents. UPPP was the predominant OSAS treatment before continuous positive airway pressure (CPAP) devices became widely available; however, the role of UPPP has been questioned because of side effects, complications, and a lack of OSAS treatment efficacy.
Explore this issue:June 2016
Study design: Prospective randomized controlled trial of 65 patients, with two parallel arms; the intervention group (32 patients) underwent surgery between June 2007 and May 2011, while the controls (33 patients) had no treatment.
Setting: Otorhinolaryngology Department of the Karolinska University Hospital in Huddinge, Stockholm, Sweden.