Explore this issue:September 2018
What is the impact of oncogene panel results on the surgical management of indeterminate thyroid nodules (ITNs)?
OP evaluation was associated with higher rates of total thyroidectomy and central lymph node dissection without increasing the yield of malignancy or decreasing the rate of completion thyroidectomy.
Background: Several molecular marker tests are commercially available to characterize thyroid nodules with indeterminate cytology. Rule-out tests may avoid unnecessary diagnostic surgery, while rule-in tests may avoid the need for a completion thyroidectomy by identifying cancer before a diagnostic procedure. Total thyroidectomies may put patients at higher surgical risks to gain no clinical benefit.