Does topical application of ofloxacin to the intact tympanic membrane (TM) compare to systemic administration?
Explore this issue:October 2010
Background: Acute otitis media (AOM) is routinely treated with systemic antibiotics, which have been linked to antibiotic-resistant strains of bacteria. Generally, topical therapy is considered appropriate if the TM is nonintact and permits solutions placed in the external auditory canal to enter the middle ear space. Children with AOM, however, have an intact TM.
Study design: A prospective, controlled animal study| | | Next → | Single Page