What is the distribution of recurrent respiratory papillomatosis (RRP) lesions in previously untreated patients at initial presentation across a specified 21 laryngeal anatomic regions?
In untreated RRP patients presenting to three laryngology clinics, males had more anatomic sites affected by papilloma than females and the membranous vocal folds were most likely to be affected.
Explore this issue:January 2018
Background: RRP a relatively rare chronic disease caused by human papillomavirus (HPV) infection, is the most common benign tumor of the larynx. To date, RRP lesion distribution within the larynx has been reported only for cohorts in which some or all patients received treatment prior to analyses. Because the link between RRP treatment and recurrence is not well understood, this may mask the true natural distribution and progression of the disease.
Study design: Multi-institutional, retrospective case series of 83 previously untreated patients diagnosed with adult-onset RRP between 2007 and 2017.