How accurate is videostroboscopy (VS) in differentiating early glottic cancer from noninvasive lesions?
Bottom Line: Although VS is able to identify almost all patients with cancer, only approximately two-thirds of patients with noninvasive lesions are correctly identified as not having cancer. Authors believe that VS remains the gold standard as a screening procedure for assessing glottic lesions but should be supplemented by further diagnostic procedures due to its inability to correctly identify patients who do not have cancer.
Explore this issue:September 2016
Background: Almost half of all laryngeal cancers are located in the glottis. Premalignant lesions (dysplasia or laryngeal intraepithelial neoplasia [LIN]) often appear as white or red areas, but they may also be benign. While VS may not provide additional information for obvious cancer, for smaller lesions it will raise the suspicion of malignant invasion into the deeper layers of the mucosa.
Study design: Systematic review and meta-analysis of five studies with a total of 307 patients.