Caution should be used when considering biologics such as dupilumab as a first-line therapy for recalcitrant CRSwNP when viable revision surgical alternatives exist.
Extended Modulator Therapy Does Not Improve Olfactory Dysfunction in Patients with Cystic Fibrosis-Related Chronic Rhinosinusitis
Olfactory dysfunction (OD) in adults with CF did not improve in a clinically relevant manner after two years of ETI.
Temperature-Controlled Radiofrequency Neurolysis of the Posterior Nasal Nerve Effective Long Term in Patients with Chronic Rhinitis
What is the long-term safety and effectiveness of temperature-controlled radiofrequency neurolysis of the posterior nasal nerve in patients with chronic rhinitis?
Objective Patterns of Olfactory Impairment and Reduced Olfactory Threshold Shown in Patients with Uncontrolled Chronic Rhinosinusitis
Patients with uncontrolled chronic rhinosinusitis (CRS) demonstrate distinct patterns of olfactory impairment, and a reduced olfactory threshold is highly associated with uncontrolled CRS.
Platelet-to-Lymphocyte Ratio Might Predict Response to Dupilumab in Patients with Chronic Rhinosinusitis with Nasal Polyps
Platelet-to-lymphocyte ratio (PLR) might have a predictive value in patients with chronic rhinosinusitis with nasal polyps in terms of treatment response to dupilumab, particularly PLR above 131.2.
Over-the-Counter Preparation Shows Promise in Biofilm-Associated Chronic Rhinosinusitis Treatment
Nasodine, an over-the-counter preparation, shows effective antibiofilm agent that is highly active against biofilms and holds promise for the management of sinonasal biofilms in CRS.
Evaluation of YouTube Endoscopy Videos Reveals a Quality Deficiency
YouTube, recently cited as the most used video forum for surgical preparation among residents and medical students, suggests videos to users based on an algorithm that prioritizes video metrics over quality.
Local Nasal Immunotherapy Safe, Effective for Allergic Rhinitis
Local nasal immunotherapy is a safe alternative immunotherapy route that improves clinical symptoms, reduces medication usage, and increases the nasal provocation threshold.
Novel Medication Delivery System Benefits Postsurgical and Nonsurgical Patients with Chronic Rhinosinusitis with Nasal Polyps
Findings suggest that an exhalation delivery system with fluticasone reduces symptoms and improves quality of life in patients with recurrent symptoms after sinus surgery and patients who have never had surgery.
Intrathecal Gd-MRC demonstrated to be the most useful diagnostic method to detect CSF rhinorrhea
A multi-database search comparing the diagnostic accuracy among seven radiological methods in analyzing CSF rhinorrhea showed Gd-MRC to be significantly superior to other imaging methods regarding sensitivity and accuracy.
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