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July 2013Knowledge is power, an aphorism usually cited in politics and war, can now be applied to the pre-operative diagnosis of midline neck masses in children. In the largest study of its kind to date, researchers have identified three ultrasound features that have 100 percent positive predictive value (PPV) in predicting the presence of thyroglossal duct cysts (TGDCs) over dermoid cysts—two masses that often mimic each other, complicating pre-operative planning and family counseling.