The preliminary results of the study, which the researchers presented at a 2008 Triological Society section meeting, indicate that 17 patients had at least a partial response to therapy. Eight patients had a complete response after two cycles, and four more showed a complete response after three cycles of induction chemotherapy. Five patients attained a complete response only after chemoradiation. One patient who did not respond to induction therapy refused surgery, went off-study, and subsequently died from the disease.
With a median follow-up of 29.6 months for the 17 patients who remained on-study, two patients have been lost to follow-up, fourteen are relapse-free, and one patient suffered a distant recurrence.
Three patients developed neuropathy during induction therapy, but the side effect resolved itself. Twelve patients required a temporary PEG tube, and three (17%) individuals required a permanent tube due to unresolved dysphagia.| ← Previous | | | Next → | Single Page