ENTtoday
  • Home
  • COVID-19
  • Practice Focus
    • Allergy
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Departments
    • Issue Archive
    • TRIO Best Practices
      • Allergy
      • Facial Plastic/Reconstructive
      • Head and Neck
      • Laryngology
      • Otology/Neurotology
      • Pediatric
      • Rhinology
      • Sleep Medicine
    • Career Development
    • Case of the Month
    • Everyday Ethics
    • Health Policy
    • Legal Matters
    • Letter From the Editor
    • Medical Education
    • Online Exclusives
    • Practice Management
    • Resident Focus
    • Rx: Wellness
    • Special Reports
    • Tech Talk
    • Viewpoint
    • What’s Your O.R. Playlist?
  • Literature Reviews
    • Allergy
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Events
    • Featured Events
    • TRIO Meetings
  • Contact Us
    • About Us
    • Editorial Board
    • Triological Society
    • Advertising Staff
    • Subscribe
  • Advertise
    • Place an Ad
    • Classifieds
    • Rate Card
  • Search

Is Endoscopic Sinus Surgery Beneficial Post Lung Transplant in Cystic Fibrosis Patients?

by Amy Hughes, MD, and Eelam A. Adil, MD, MBA • December 14, 2020

  • Tweet
  • Email
Print-Friendly Version

TRIO Best PracticeTRIO Best Practice articles are brief, structured reviews designed to provide the busy clinician with a handy outline and reference for day-to-day clinical decision making. The ENTtoday summaries below include the Background and Best Practice sections of the original article. To view the complete Laryngoscope articles free of charge, visit Laryngoscope.

You Might Also Like

  • What Is the Role of Endoscopic Sinus Surgery In Patients With Cystic Fibrosis?
  • Endoscopic Sinus Surgery Improves QoL in Patients with Minimal Disease
  • Does Endoscopic Sinus Surgery Improve Olfaction in Nasal Polyposis?
  • CRS Impact on Patients with Cystic Fibrosis Not Well Known
Explore This Issue
December 2020

Background

Cystic fibrosis (CF) is an autosomal recessive disorder caused by a genetic mutation in the gene that encodes the cystic fibrosis transmembrane conductance regulator (CFTR) protein. There are numerous known mutations of the CFTR gene, with ΔF508 being the most common. A defect in the CFTR gene leads to impaired ion transport across cell membranes and results in tenacious secretions that cause significant aerodigestive morbidity. As a result of pulmonary injury, CF is the most common indication for pediatric lung transplantation in the U.S. The paranasal sinuses are thought to be an upper airway bacterial reservoir of infection that can spread to the lower airway and cause lung allograft infection. Poor transplant outcomes are associated with bacterial colonization and infection. The purpose of this review is to evaluate the most recent evidence regarding the role of endoscopic sinus surgery (ESS) following lung transplantation in patients with CF.

Best Practice

Based on the current literature, there is evidence to suggest a beneficial role of ESS post lung transplantation in CF patients with and without nasal polyposis. Extensive ESS following transplantation aimed at eradicating paranasal sinus colonization may decrease lung allograft infection and thereby improve survival. CF patients may be too unhealthy to consider extensive ESS prior to transplantation.

The literature regarding post-transplantation outcomes may be biased as they are limited to a single institution’s retrospective experience. It would be useful if other high-volume lung transplant groups published their experiences with ESS in relation to CF lung transplantation

Filed Under: Rhinology, TRIO Best Practices Tagged With: cystic fibrosis, surgery, treatmentIssue: December 2020

You Might Also Like:

  • What Is the Role of Endoscopic Sinus Surgery In Patients With Cystic Fibrosis?
  • Endoscopic Sinus Surgery Improves QoL in Patients with Minimal Disease
  • Does Endoscopic Sinus Surgery Improve Olfaction in Nasal Polyposis?
  • CRS Impact on Patients with Cystic Fibrosis Not Well Known

The Triological SocietyENTtoday is a publication of The Triological Society.

The Laryngoscope
Ensure you have all the latest research at your fingertips; Subscribe to The Laryngoscope today!

Laryngoscope Investigative Otolaryngology
Open access journal in otolaryngology – head and neck surgery is currently accepting submissions.

Classifieds

View the classified ads »

TRIO Best Practices

View the TRIO Best Practices »

Top Articles for Residents

  • Do Training Programs Give Otolaryngology Residents the Necessary Tools to Do Productive Research?
  • Why More MDs, Medical Residents Are Choosing to Pursue Additional Academic Degrees
  • What Physicians Need to Know about Investing Before Hiring a Financial Advisor
  • Tips to Help You Regain Your Sense of Self
  • Should USMLE Step 1 Change from Numeric Score to Pass/Fail?
  • Popular this Week
  • Most Popular
  • Most Recent
    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment
    • Vertigo in the Elderly: What Does It Mean?
    • Experts Delve into Treatment Options for Laryngopharyngeal Reflux
    • Some Laryngopharyngeal Reflux Resists PPI Treatment
    • Weaning Patients Off of PPIs
    • Vertigo in the Elderly: What Does It Mean?
    • New Developments in the Management of Eustachian Tube Dysfunction
    • Some Laryngopharyngeal Reflux Resists PPI Treatment
    • Eustachian Tuboplasty: A Potential New Option for Chronic Tube Dysfunction and Patulous Disease
    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment
    • Podcasts Becoming More Popular Method of Education for Otolaryngologists
    • How to Embrace Optimism in the Midst of the COVID-19 Pandemic
    • Tips on How to Approach Conversations with Patients about the COVID-19 Vaccine
    • Steps You Should Take to Protect Your Voice and Hearing During Telemedicine Sessions
    • Routine Postoperative Adjunct Treatments Unnecessary for Idiopathic Cerebrospinal Fluid Leaks

Polls

Have you spoken with your patients about receiving the COVID-19 vaccine?

View Results

Loading ... Loading ...
  • Polls Archive
  • Home
  • Contact Us
  • Advertise
  • Privacy Policy
  • Terms of Use

Visit: The Triological Society • The Laryngoscope • Laryngoscope Investigative Otolaryngology

Wiley
© 2021 The Triological Society. All Rights Reserved.
ISSN 1559-4939

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.