• Home
  • Practice Focus
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
    • How I Do It
    • TRIO Best Practices
  • Business of Medicine
    • Health Policy
    • Legal Matters
    • Practice Management
    • Tech Talk
    • AI
  • Literature Reviews
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Career
    • Medical Education
    • Professional Development
    • Resident Focus
  • ENT Perspectives
    • ENT Expressions
    • Everyday Ethics
    • From TRIO
    • The Great Debate
    • Letter From the Editor
    • Rx: Wellness
    • The Voice
    • Viewpoint
  • TRIO Resources
    • Triological Society
    • The Laryngoscope
    • Laryngoscope Investigative Otolaryngology
    • TRIO Combined Sections Meetings
    • COSM
    • Related Otolaryngology Events
  • Search

Should Oral Antibiotics Be Prescribed Routinely Post-Endoscopic Sinus Surgery?

by By Christopher J. Chin, MD, Kalpesh Hathi, BScKin, Mitchell McDonough, BSc, and Leigh J. Sowerby, MD • September 19, 2021

  • Tweet
  • Click to email a link to a friend (Opens in new window) Email
Print-Friendly Version

TRIO Best PracticeTRIO Best Practice articles are brief, structured reviews designed to provide the busy clinician with a handy outline and reference for day-to-day clinical decision making. The ENTtoday summaries below include the Background and Best Practice sections of the original article. To view the complete Laryngoscope article free of charge, visit Laryngoscope.

You Might Also Like

  • Topical Antibiotic Use Following Sinus Surgery
  • Is Endoscopic Sinus Surgery Beneficial Post Lung Transplant in Cystic Fibrosis Patients?
  • What Is the Role of Endoscopic Sinus Surgery In Patients With Cystic Fibrosis?
  • Is Cocaine a Safe Topical Agent For Use During Endoscopic Sinus Surgery?
Explore This Issue
September 2021

BACKGROUND

© PhuShutter / shutterstock.com

© PhuShutter / shutterstock.com

Chronic rhinosinusitis (CRS) is a common condition associated with significant patient morbidity and healthcare costs. Medically refractory CRS is often treated surgically with endoscopic sinus surgery (ESS).
The need for routine use of oral antibiotics post-sinus surgery is controversial. If patients experience equivalent outcomes with and without postoperative antibiotics, then reducing routine use could positively impact antibiotic-resistance trends and healthcare costs, while avoiding the systemic side effects of antibiotics. The goal of this review is to determine if oral antibiotics should be routinely prescribed following ESS. Of note, this paper excluded studies that included macrolide antibiotics, as well as doxycycline, as their use in CRS is frequently for their anti-inflammatory properties.

BEST PRACTICE

For uncomplicated ESS cases, the current level 1 evidence does not support the routine use of oral antibiotics post-operatively. Future studies with larger sample sizes would overcome the limitations of current literature, which is characterized by small sample size and variable antibiotic regimen.

Filed Under: Rhinology, Rhinology, TRIO Best Practices Tagged With: clinical research, treatmentIssue: September 2021

You Might Also Like:

  • Topical Antibiotic Use Following Sinus Surgery
  • Is Endoscopic Sinus Surgery Beneficial Post Lung Transplant in Cystic Fibrosis Patients?
  • What Is the Role of Endoscopic Sinus Surgery In Patients With Cystic Fibrosis?
  • Is Cocaine a Safe Topical Agent For Use During Endoscopic Sinus Surgery?

The Triological SocietyENTtoday is a publication of The Triological Society.

Polls

Do you use AI-powered scribes for documentation?

View Results

Loading ... Loading ...
  • Polls Archive

Top Articles for Residents

  • Applications Open for Resident Members of ENTtoday Edit Board
  • How To Provide Helpful Feedback To Residents
  • Call for Resident Bowl Questions
  • New Standardized Otolaryngology Curriculum Launching July 1 Should Be Valuable Resource For Physicians Around The World
  • Do Training Programs Give Otolaryngology Residents the Necessary Tools to Do Productive Research?
  • Popular this Week
  • Most Popular
  • Most Recent
    • How to: Positioning for Middle Cranial Fossa Repair of Superior Semicircular Canal Dehiscence

    • Endoscopic Ear Surgery: Advancements and Adoption Challenges 

    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment

    • Rating Laryngopharyngeal Reflux Severity: How Do Two Common Instruments Compare?

    • Otolaryngologists Are Still Debating the Effectiveness of Tongue Tie Treatment

    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment

    • Rating Laryngopharyngeal Reflux Severity: How Do Two Common Instruments Compare?

    • Is Middle Ear Pressure Affected by Continuous Positive Airway Pressure Use?

    • Otolaryngologists Are Still Debating the Effectiveness of Tongue Tie Treatment

    • Complications for When Physicians Change a Maiden Name

    • The Importance of Time Away
    • Endoscopic Ear Surgery: Advancements and Adoption Challenges 
    • Reflections from a Past President of the Triological Society
    • ENT Surgeons Explore the Benefits and Challenges of AI-Powered Scribes: Revolutionizing Documentation in Healthcare
    • How To: Open Expansion Laryngoplasty for Combined Glottic and Subglottic Stenosis

Follow Us

  • Contact Us
  • About Us
  • Advertise
  • The Triological Society
  • The Laryngoscope
  • Laryngoscope Investigative Otolaryngology
  • Privacy Policy
  • Terms of Use
  • Cookies

Wiley

Copyright © 2025 by John Wiley & Sons, Inc. All rights reserved, including rights for text and data mining and training of artificial technologies or similar technologies. ISSN 1559-4939