Hearing loss in the ITD group was strictly related to the progression of Meniere’s disease, that is, only in patients who had poor control of vertigo. For the ITG group, 12 percent had increased hearing loss likely attributable to gentamicin.
Bottom line: In patients with refractory, unilateral Meniere’s disease, low-dose intratympanic gentamicin is relatively effective in controlling vertigo and has a low incidence (12 percent) of hearing loss. Intratympanic dexamethasone 4 mg/mL is less effective in controlling vertigo, similar to placebo, and did not influence hearing loss.
Reference: Casani AP, Piaggi P, Cerchiai N, et al. Intratympanic treatment of intractable unilateral Meniere’s disease: gentamicin or dexamethasone? A randomized controlled trial. Otolaryngol Head Neck Surg. 2012;146(3):430-437.| ← Previous | | | Next → | Single Page