The cause of MFH is unknown, but it is believed that a genetic abnormality on the short arm of chromosome 19 or loss of chromosome 13 may play a role.
The disease also has been linked to radiation treatment for breast cancer, retinoblastoma, Hodgkin’s disease, nasopharyngeal carcinomas, and other head and neck malignancies.
Patients often present with a painless soft tissue mass in the neck that, before biopsy, may be confused with lymphomas, other soft tissue sarcomas, and metastatic carcinomas. Those on the scalp are often mistaken for desmoplastic melanomas or atypical fibroxanthomas. Those arising in the nose, nasopharynx, and paranasal sinuses can be confused with other sinonasal malignancies. | ← Previous | | | Next → | Single Page