Mounting evidence suggests that bacterial biofilms play a role in chronic inflammatory infections of the middle ear and sinuses. Whether these biofilms actually cause chronic ear and sinus infections remains unproven, but it is increasingly shown from a number of animal studies and a recently published human study that biofilms are present in these chronic otolaryngologic conditions.
Explore this issue:January 2007
Biofilms are a relatively novel way of looking at bacteria, said Martin Desrosiers, MD, Department of Otolaryngology, Head and Neck Surgery at McGill University in Montreal, who, along with his colleagues, has examined the role of biofilms in chronic sinusitis. A number of people [studying] chronic sinusitis have found that there are biofilms that are present, he said. So this is quite a revelation that gives us a new therapeutic target.
Although much of the published data showing the presence of biofilms in chronic sinusitis and chronic otitis media have been in animal studies, a recently published study in humans now adds weight to the evidence of the presence of biofilms in these chronic conditions.| | | Next → | Single Page