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AAO-HNS14: New Assessment Methods for Thyroid Nodules

by Thomas R. Collins • November 4, 2014

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Dr. Witt said that it’s an exciting time in thyroid surgery. “Few fields in medicine rival the dynamism of modern thyroid diagnosis, management, and prognostication,” he said. “Molecular alteration testing, next generation sequencing, and gene expression classifier testing are the most important advances in the diagnosis and management of cancer since the introduction of fine needle aspiration cytology a half-century ago.”

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Explore This Issue
November 2014

Keith Forwith, MD, PhD, an otolaryngologist at Advanced ENT and Allergy in Louisville, Ky., who sat in on the session, said some of the tests “aren’t ready for mainstream private practice outside of an academic setting, but they’re getting closer.” Afirma is now widely available, and he’s used it some, but he added, “Some of the patients that I’ve done it on have been hit with a $1,400 bill, so you have to be careful about whether that’s covered or not covered.” Also, whether to use such testing has to depend in part on the sophistication of the patient, he said. “This is not for an uneducated patient who has difficulty sorting through the science of it.”

Take-Home Points

  • Molecular testing of thyroid nodules is becoming a useful tool in helping head and neck surgeons make surgery decisions when cytology yields unclear results.
  • Another new approach—the Afirma GEC—is strong in its negative predictive value and is powerful as a “rule out” test.
  • It’s important to use genetic tests in the right context.
  • Patient consultation in cases of thyroid surgery is an important component of care.

Pages: 1 2 3 | Single Page

Filed Under: Features, Head and Neck, Practice Focus Tagged With: AAO-HNS, thyroid noduleIssue: November 2014

You Might Also Like:

  • Large Thyroid Nodules Carry Higher Pretest Malignancy Probability
  • Molecular Testing for Thyroid Nodules Recommended as Adjunct to Fine Needle Aspiration
  • What Is the Utility of Genetic Testing in Indeterminate Thyroid Nodules?
  • New Guidelines Developed to Manage Thyroid Nodules and Thyroid Cancer

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