What is the pathological evolution and natural history of laryngeal dysplasia, and what is the role of serial excisions in dysplasia grade regression in long-term follow-up?
Background: Vocal fold leukoplakia prevalence in the United States is estimated at 10.2 and 2.1 per 100,000 in males and females, respectively. Pathologic correlation is important because leukoplakia exists on a spectrum from benign hyperkeratosis to premalignant dysplasia to invasive squamous cell carcinoma. As such, most surgeons are reluctant to manage newly diagnosed leukoplakia with watchful waiting, preferring instead to biopsy.
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April 2016Study design: Retrospective case series of 31 patients treated for vocal fold dysplasia between 1994 and 2013.
Setting: Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine, Houston.
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