ENTtoday
  • Home
  • COVID-19
  • Practice Focus
    • Allergy
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Departments
    • Issue Archive
    • TRIO Best Practices
      • Allergy
      • Facial Plastic/Reconstructive
      • Head and Neck
      • Laryngology
      • Otology/Neurotology
      • Pediatric
      • Rhinology
      • Sleep Medicine
    • Career Development
    • Case of the Month
    • Everyday Ethics
    • Health Policy
    • Legal Matters
    • Letter From the Editor
    • Medical Education
    • Online Exclusives
    • Practice Management
    • Resident Focus
    • Rx: Wellness
    • Special Reports
    • Tech Talk
    • Viewpoint
    • What’s Your O.R. Playlist?
  • Literature Reviews
    • Allergy
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Events
    • Featured Events
    • TRIO Meetings
  • Contact Us
    • About Us
    • Editorial Board
    • Triological Society
    • Advertising Staff
    • Subscribe
  • Advertise
    • Place an Ad
    • Classifieds
    • Rate Card
  • Search

Triological Society Names Winners of Mosher, Fowler Awards

by Thomas R. Collins • June 8, 2015

  • Tweet
  • Email
Print-Friendly Version

She said she hopes the findings, which her group intends to refine—possibly by using video images and images of less severe paralysis—can help guide reconstruction. “We can’t attack all of the deficits at once,” Dr. Ishii said. “And this helps us to start to structure where we need to focus our attention to get the greatest outcome for the patient.”

You Might Also Like

  • Mosher and Fowler Awards Honor Legacies of Pioneers in Otolaryngology
  • COSM13: Triological Society Awards Excellence in Candidate Theses
  • Triological Society Presents Otolaryngology Awards at 2014 Combined Sections Meeting
  • Triological Society New Fellow Thesis Award Winners
Explore This Issue
June 2015

Edmund Prince Fowler Award

In another honor given at the meeting this year, the Fowler Award recognizing excellence among theses in basic science, was presented to Bradford Woodworth, MD, assistant professor of surgery and director of otolaryngology research at the University of Alabama in Birmingham, for his findings on resveratrol and mucociliary clearance.

Dr. Woodworth

Dr. Woodworth

In the study, Dr. Woodworth and his team created a model of hypoxia-induced dysfunction of cystic fibrosis transmembrane conductance regulator (CFTR) and, within that model, found that resveratrol—a non-flavonoid polyphenol—can help reverse this dysfunction.

Mucociliary clearance, the process of capturing bacteria and other airborne threats and removing them from the body, is the airway’s main innate defense against disease. It depends on proper function of the CFTR chloride transport channel. When the channel is blocked, the airway surface liquid gets dehydrated, leading to a blockage of mucociliary clearance, overgrowth of bacteria, and airway infections.

Researchers found that they could use oxygen restriction to deplete airway surface liquid with an underlying mechanism similar to cystic fibrosis, making it a useful model in which to study resveratrol’s effects in preparation for a clinical trial.

Furthermore the researchers found that they could activate transepithelial chloride transport using resveratrol, ultimately increasing the depth of the airway surface liquid. “The hypoxia-induced model is an acquired CFTR dysfunction model,” Dr. Woodworth said. “It is ameliorated and mitigated by resveratrol, and this results in improved epithelial function and ion transport.”

The findings suggest this could be a worthwhile therapeutic approach. “Essentially, it’s a good model to say, ‘Hey, we have these hypoxic defects. You can have acquired CFTR deficiency and sinus disease, and maybe chloride secretagogues could be a good approach, an innovative approach, to overcoming acquired CFTR defects in sinus disease.”

Pages: 1 2 | Single Page

Filed Under: Features Tagged With: COSM, Fowler, MosherIssue: June 2015

You Might Also Like:

  • Mosher and Fowler Awards Honor Legacies of Pioneers in Otolaryngology
  • COSM13: Triological Society Awards Excellence in Candidate Theses
  • Triological Society Presents Otolaryngology Awards at 2014 Combined Sections Meeting
  • Triological Society New Fellow Thesis Award Winners

The Triological SocietyENTtoday is a publication of The Triological Society.

The Laryngoscope
Ensure you have all the latest research at your fingertips; Subscribe to The Laryngoscope today!

Laryngoscope Investigative Otolaryngology
Open access journal in otolaryngology – head and neck surgery is currently accepting submissions.

Classifieds

View the classified ads »

TRIO Best Practices

View the TRIO Best Practices »

Top Articles for Residents

  • Do Training Programs Give Otolaryngology Residents the Necessary Tools to Do Productive Research?
  • Why More MDs, Medical Residents Are Choosing to Pursue Additional Academic Degrees
  • What Physicians Need to Know about Investing Before Hiring a Financial Advisor
  • Tips to Help You Regain Your Sense of Self
  • Should USMLE Step 1 Change from Numeric Score to Pass/Fail?
  • Popular this Week
  • Most Popular
  • Most Recent
    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment
    • Vertigo in the Elderly: What Does It Mean?
    • Experts Delve into Treatment Options for Laryngopharyngeal Reflux
    • A Look at the Latest Research on Subglottic Stenosis
    • Weaning Patients Off of PPIs
    • Vertigo in the Elderly: What Does It Mean?
    • New Developments in the Management of Eustachian Tube Dysfunction
    • Some Laryngopharyngeal Reflux Resists PPI Treatment
    • Eustachian Tuboplasty: A Potential New Option for Chronic Tube Dysfunction and Patulous Disease
    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment
    • Did You Receive COVID-19 Relief? Here Are Reporting Considerations for 2021
    • Otolaryngology Experts Share Best Practices in Five Areas
    • How Climate Change May Be Affecting Sleep Patterns for Adults and Children
    • Laryngologists Discuss Tough Tracheostomy Choices During COVID-19 Era
    • Head and Neck Cancer: Experts Discuss How to Improve Surgery Quality and Value

Polls

Did you receive funding from the CARES Act or Paycheck Protection Program?

View Results

Loading ... Loading ...
  • Polls Archive
  • Home
  • Contact Us
  • Advertise
  • Privacy Policy
  • Terms of Use

Visit: The Triological Society • The Laryngoscope • Laryngoscope Investigative Otolaryngology

Wiley
© 2021 The Triological Society. All Rights Reserved.
ISSN 1559-4939

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.