The interaction between tobacco exposure and HPV infection in the context of OPSCC has significant implications for standard of care treatment regimens.
Is It Time to De-Escalate Radiation Therapy in Patients with HPV+ HNC?
Radiation therapy has a host of drawbacks, including long-term side effects and even treatment-related morbidity in some cases.
Post-Treatment Persistence of Oral HPV in Head and Neck Cancer Predicts Recurrence, Death
Analysis of tumor type HPV DNA has considerable promise as a biomarker for treatment response and risk of progression.
Should the Contralateral Tonsil Be Removed in Cases of HPV-Positive Squamous Cell Carcinoma of the Tonsil?
The contralateral tonsil should routinely be removed in cases of suspected or known unilateral HPV+ TSCC.
Is it Safe to Kiss in Era of HPV Head and Neck Cancer ‘Epidemic’?
Patients in both the general (noncancer) and HPV-OPC populations may enquire whether they should avoid open-mouth kissing to prevent either acquiring or transmitting oral HPV infection.
In OPSCC, Tumor Location and T Stage More Significant than HPV Status
However, there was no significantly different incidence of CBNM between HPV-positive and HPV-negative patients
Experts Discuss HPV-Positive Head and Neck Cancer
De-intensifying both surgical and radiation treatment can be effective in some patients
New Staging System Proposed for HPV-Related Oropharyngeal Cancer
Researchers propose a new staging system for human papillomavirus-related oropharyngeal cancers based on findings from the International Collaboration on Oropharyngeal cancer Network for Staging (ICON-S) study.
Optimizing Treatment for Oropharyngeal Cancer
The possibility of de-escalating treatment is being evaluated in a clinical trial of participants with HPV-positive stage III-IVA oropharyngeal cancer
Risk of Oral HPV Infections and OSCC Linked to Cumulative Exposure to Oral Sexual Activity
Emerging evidence shows that the demographic profile of groups at risk of oral HPV infections and OSCC is linked to cumulative exposure to oral sexual activity