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Flexible Ossicular Reconstruction Prosthesis Allows for Ease of Placement in Temporal Bone

November 17, 2016

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Photos of specimens implanted with different adjustable ossicular replacement prostheses. Clockwise from upper left: intact, adjustable partial ossicular replacement prosthesis (A-PORP), PORP, incus PORP, adjustable total ossicular replacement prosthesis, A-PORP under laser Doppler vibrometry.

Photos of specimens implanted with different adjustable ossicular replacement prostheses. Clockwise from upper left: intact, adjustable partial ossicular replacement prosthesis (A-PORP), PORP, incus PORP, adjustable total ossicular replacement prosthesis, A-PORP under laser Doppler vibrometry.
© 2016 The American Laryngological, Rhinological and Otological Society, Inc.

Does an adjustable ossicular replacement prosthesis (ORP) allow for easier optimal device placement?

BOTTOM LINE
An adjustable ossicular replacement prostheses (ORP) allows for in situ length adjustment and easier alignment and tension optimization in ossiculoplasty, and they represent a promising new direction for the devices.

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November 2016

Background: Ossicular reconstruction surgery is a commonly performed procedure in the case of a discontinuous or fixed ossicular chain, and there exists a variety of ossicular replacement prostheses (ORPs) that have been designed for this purpose. Previous studies have examined the relative efficacy of different prosthesis designs, but the results of these studies vary widely. A number of studies have shown that the performance of an implanted ORP depends highly on its position, alignment, and tension between the tympanic membrane (TM) and the stapes head or footplate. Because of this, there has been interest in the design of adjustable-length prostheses that can be fit to the exact anatomy of an individual ear to optimize placement.

The goal of this study was to establish a basis for future work on the design of a new adjustable ORP by testing whether the addition of this flexible element degrades the acoustic performance of the prosthesis relative to standard prostheses commonly used for ossiculoplasty, such as a nonadjustable titanium ORP or a sculpted autologous incus prosthesis (I-PORP).

Study design: A 3D laser Doppler vibrometry system was used to simultaneously measure vibration velocity along three orthogonal axes, and the resultant 3D motion of a single point on the stapes from 0.2 to 20 kHz is reported for the first time. These measurements were performed on both normal ossicular chains and those reconstructed using the new adjustable ORP, a standard ORP, and an a sculpted autologous incus prosthesis I-PORP placed between the stapes head and either the TM or the manubrium.

Synopsis: In this study, a novel ORP with a flexible element that may allow for length adjustment in situ is presented and tested for acoustic performance. The device has an initial compact length that makes it easy to insert and align through the facial recess before the flexible element is expanded to achieve optimal tension.

The stapes velocity transfer function (SVTF), defined as the stapes velocity divided by ear canal pressure, was calculated for all cases. In a comparison of the 3D- SVTF and its three orthogonal components for an intact and a PORP case, two features were evident: first, although the component SVTFs of the intact case have prominent localized resonances, the 3D-SVTF is smoother because those resonances occur at different frequencies.

The authors say this also suggests that the stapes has several different vibration modes over the measured frequency range; second, the relationship between the component SVTFs differs greatly between the intact and PORP cases, which indicates that the PORP affects not only the stapes vibration magnitude but also the vibration mode.

No significant difference was found between the acoustic performance of the new A-ORP designs and a conventional titanium PORP or an I-PORP.

Citation: Gottlieb PK, Li X, Monfared A, Blevins N, Puria S. First results of a novel adjustable-length ossicular reconstruction prosthesis in temporal bones. Laryngoscope. 2016;126: 2559–2564.

Pages: 1 2 | Multi-Page

Filed Under: Literature Reviews, Otology/Neurotology Tagged With: ORP, ossicular replacement prostheses, outcome, temporal boneIssue: November 2016

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