All vascular lesions are not hemangiomas. In the old days, hemangioma was a ‘waste basket’ term for any type of vascular malformation. Unfortunately, some physicians still apply that definition, Dr. Waner commented.
Dr. Waner described a new classification system for vascular anomalies that includes three major categories: 1) hemangiomas; 2) vascular malformations; 3) vascular tumors, including RICH (rapidly involuting tumors), NICH (non-involuting tumors), and Kaposiform hemangioendothelioma. GLUT-1 (glucose transporter isoform-1) staining, a recent advance, is used to differentiate between vascular anomalies based on histopathology.
Hemangiomas hold a secret, and if we could understand why they grow and why they resolve, we might find a key for curing cancers. – -Francine Blei, MD