How accurate is diagnosis of cervical TB lymphadenitis utilizing the GeneXpert MTB/RIF assay in HIV-infected patients with palpable cervical lymph nodes?
Background: HIV infection is the most common risk factor associated with extrapulmonary TB (EPTB), with cervical tuberculosis (TB) lymphadenitis the most common manifestation. Automated liquid culture is gold standard for TB diagnosis, but it is labor intensive. In 2010, the WHO endorsed the GeneXpert MTB/RIF assay for pulmonary TB diagnosis in HIV-infected patients from developing countries.
Explore this issue:June 2014
Study design: Prospective, diagnostic test study of 68 consecutive patients aged 16 years old and older with cervical lymphadenopathy between January 2011 and March 2013.
Setting: Center for Research in Infectious Diseases at the National Institute of Respiratory Diseases, Mexico City.