What is the efficacy and safety of a five-day moxifloxacin regimen in the treatment of acute bacterial rhinosinusitis (ABRS)? Background: There is a lack of clarity regarding the role of antimicrobials in ABRS treatment. Although current guidelines encourage the use of antimicrobials, it is difficult to identify appropriate patients. Additionally, there would be benefits to reducing […]
Secondhand Smoke Increases Chronic Rhinosinusitis Risk
Is exposure to secondhand smoke a risk factor for chronic rhinosinusitis (CRS)? Background: There are surprisingly few studies that address the association between secondhand smoke (SHS) and sinusitis, and most use fairly weak criteria for sinusitis, such as a patient’s having checked “sinusitis” on a health questionnaire. There are, however, several studies that address the effects […]
Avastin Treatment for Hereditary Hemorrhagic Telangiectasia Epistaxis
Can the vascular endothelial growth factor (VEGF) inhibitor bevacizumab (Avastin) treat hereditary hemorrhagic telangiectasia (HHT) epistaxis? Background: HHT is an autosomal dominant disorder involving abnormal blood vessel development. An estimated 90 percent of HHT patients have epistaxis which can lead to significant blood loss requiring IV iron, emergency room visits and blood transfusions. Surgical outcomes […]
Panel Debates when to Use an Endoscopic Approach to Sinus Surgery
Endoscopic sinus surgery is an approach commonly used by otolaryngologists–head and neck surgeons, but for what indications is it the best technique to use—and how has its use evolved over the years?
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