Several treatments for allergy-related disease have high-quality evidence to support them, according to panelists at a seminar in Chicago at the annual meeting of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS), which focused on evidence-based medicine as the model applies to allergy.
Explore this issue:March 2009
Importantly, evidence of high quality, such as randomized, placebo-controlled trials, supports certain treatments that are established and others that are newer. For example, the evidence for allergy immunotherapy desensitization is quite strong, and it is also promising for novel treatments-for instance, monoclonal antibodies such as omalizumab (Xolair) for treatment-resistant disease and desensitization therapy for aspirin-exacerbated respiratory disease (AERD).
There is a lot of misinformation that we need to try to clarify in an effort to give recommendations about how to manage patients that is based on scientific merit, said Richard C. Haydon, MD, in a phone interview. In the last 10 to 12 years, much more attention has been paid to the science behind the management of allergy patients than before. The literature and guidelines are available in many different subjects related to allergy. We are paying attention to the evidence-based literature.