ENTtoday
  • Home
  • COVID-19
  • Practice Focus
    • Allergy
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Departments
    • Issue Archive
    • TRIO Best Practices
      • Allergy
      • Facial Plastic/Reconstructive
      • Head and Neck
      • Laryngology
      • Otology/Neurotology
      • Pediatric
      • Rhinology
      • Sleep Medicine
    • Career Development
    • Case of the Month
    • Everyday Ethics
    • Health Policy
    • Legal Matters
    • Letter From the Editor
    • Medical Education
    • Online Exclusives
    • Practice Management
    • Resident Focus
    • Rx: Wellness
    • Special Reports
    • Tech Talk
    • Viewpoint
    • What’s Your O.R. Playlist?
  • Literature Reviews
    • Allergy
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Events
    • Featured Events
    • TRIO Meetings
  • Contact Us
    • About Us
    • Editorial Board
    • Triological Society
    • Advertising Staff
    • Subscribe
  • Advertise
    • Place an Ad
    • Classifieds
    • Rate Card
  • Search

COSM14: HPV Status and Prognosis for Oropharyngeal Cancers

by Thomas R. Collins • July 1, 2014

  • Tweet
  • Email
Print-Friendly Version
HPV Epidemic

Take-Home Points

  • The number of sexual partners and the frequency with which a person performs oral sex are two key risk factors of being HPV-positive and developing oropharyngeal cancer, with young, white, college-educated males having the highest risk of oropharyngeal squamous cell carcinoma.
  • Quadrivalent vaccines have shown extremely high efficacy against the acquisition of HPV infections, but vaccine uptake rates still need improvement.
  • The use of biomarkers is being investigated to better understand how to treat different oropharyngeal cancers, but clinical trials are needed to assess these markers.
  • The main goal in the treatment of adult RRP is voice preservation, and using the right tools can make a difference.

An array of experts came together in the panel discussion “HPV in Different Subsites—Clinical Importance and Effect on Therapy” to shed light on a variety of topics concerning human papillomavirus (HPV) status, including risk factors, the effectiveness of vaccinations, the use of biomarkers to predict response to cancer treatment, and guidance on treatment of adults.

You Might Also Like

  • HPV Status an Independent Prognostic Factor for Oropharyngeal Cancer Survival
  • HPV-Oropharyngeal Cancer Link May Affect Cancer Screening and Prognosis: The link offers potential for improved detection and prevention, but more research is needed
  • Slowing the Rise of Oropharyngeal Cancers
  • Tests Emerging as Standards for Diagnosing HPV-Positive Oropharyngeal Cancer
Explore This Issue
July 2014

Panel moderator Dinesh K. Chhetri, MD, head of the Swallowing Disorders Center at the University of California at Los Angeles, said the discussion provided an up-to-date overview of a topic that’s growing in importance. “I think we should be making physicians aware of this rising HPV epidemic … how it’s changing the landscape of the diseases affected, and how we should change our management as our understanding of the HPV-related diseases increases,” he said.

The prevalence of HPV infections among the healthy U.S. population is only 1%, according to National Health and Nutrition Examination Survey data. But oropharyngeal cancer among men is on the rise, due largely to a rise in HPV-positive cancers, said Carole Fakhry, MD, MPH, assistant professor of otolaryngology-head and neck surgery at Johns Hopkins University in Baltimore.

The incidence of cervical cancer cases, which are largely caused by HPV infections as well, is on the decline and is expected to dip below cases of HPV-positive male and female oropharyngeal cancer cases in approximately 2025, Dr. Fakhry said.

Whom the Vaccine Helps

The incidence of HPV infection rises with a person’s number of sex partners, including oral sex partners (JAMA. 2012; 307:693-703). Those most at risk of oropharyngeal cancer tend to be younger, white, married, non-smokers, and college educated.

The clearest explanation for this is that younger individuals tend to report having had oral sex at the time of their first sex act, and older age groups are less likely to report this. Additionally, whites are more likely to have performed oral sex and have more oral sex partners than other races. “The oral HPV infection [rate] is related to sexual behaviors,” Dr. Fakhry said. “It’s a very low prevalence, though, in the United States. Natural history studies are just starting.”

Pages: 1 2 3 4 | Single Page

Filed Under: Features, Head and Neck, Practice Focus Tagged With: cancer, HPVIssue: July 2014

You Might Also Like:

  • HPV Status an Independent Prognostic Factor for Oropharyngeal Cancer Survival
  • HPV-Oropharyngeal Cancer Link May Affect Cancer Screening and Prognosis: The link offers potential for improved detection and prevention, but more research is needed
  • Slowing the Rise of Oropharyngeal Cancers
  • Tests Emerging as Standards for Diagnosing HPV-Positive Oropharyngeal Cancer

The Triological SocietyENTtoday is a publication of The Triological Society.

The Laryngoscope
Ensure you have all the latest research at your fingertips; Subscribe to The Laryngoscope today!

Laryngoscope Investigative Otolaryngology
Open access journal in otolaryngology – head and neck surgery is currently accepting submissions.

Classifieds

View the classified ads »

TRIO Best Practices

View the TRIO Best Practices »

Top Articles for Residents

  • Do Training Programs Give Otolaryngology Residents the Necessary Tools to Do Productive Research?
  • Why More MDs, Medical Residents Are Choosing to Pursue Additional Academic Degrees
  • What Physicians Need to Know about Investing Before Hiring a Financial Advisor
  • Tips to Help You Regain Your Sense of Self
  • Should USMLE Step 1 Change from Numeric Score to Pass/Fail?
  • Popular this Week
  • Most Popular
  • Most Recent
    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment
    • Vertigo in the Elderly: What Does It Mean?
    • Experts Delve into Treatment Options for Laryngopharyngeal Reflux
    • Weaning Patients Off of PPIs
    • Some Laryngopharyngeal Reflux Resists PPI Treatment
    • Vertigo in the Elderly: What Does It Mean?
    • New Developments in the Management of Eustachian Tube Dysfunction
    • Some Laryngopharyngeal Reflux Resists PPI Treatment
    • Eustachian Tuboplasty: A Potential New Option for Chronic Tube Dysfunction and Patulous Disease
    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment
    • Did You Receive COVID-19 Relief? Here Are Reporting Considerations for 2021
    • Otolaryngology Experts Share Best Practices in Five Areas
    • How Climate Change May Be Affecting Sleep Patterns for Adults and Children
    • Laryngologists Discuss Tough Tracheostomy Choices During COVID-19 Era
    • Head and Neck Cancer: Experts Discuss How to Improve Surgery Quality and Value

Polls

Did you receive funding from the CARES Act or Paycheck Protection Program?

View Results

Loading ... Loading ...
  • Polls Archive
  • Home
  • Contact Us
  • Advertise
  • Privacy Policy
  • Terms of Use

Visit: The Triological Society • The Laryngoscope • Laryngoscope Investigative Otolaryngology

Wiley
© 2021 The Triological Society. All Rights Reserved.
ISSN 1559-4939

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.