ENTtoday
  • Home
  • COVID-19
  • Practice Focus
    • Allergy
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Departments
    • Issue Archive
    • TRIO Best Practices
      • Allergy
      • Facial Plastic/Reconstructive
      • Head and Neck
      • Laryngology
      • Otology/Neurotology
      • Pediatric
      • Rhinology
      • Sleep Medicine
    • Career Development
    • Case of the Month
    • Everyday Ethics
    • Health Policy
    • Legal Matters
    • Letter From the Editor
    • Medical Education
    • Online Exclusives
    • Practice Management
    • Resident Focus
    • Rx: Wellness
    • Special Reports
    • Tech Talk
    • Viewpoint
    • What’s Your O.R. Playlist?
  • Literature Reviews
    • Allergy
    • Facial Plastic/Reconstructive
    • Head and Neck
    • Laryngology
    • Otology/Neurotology
    • Pediatric
    • Rhinology
    • Sleep Medicine
  • Events
    • Featured Events
    • TRIO Meetings
  • Contact Us
    • About Us
    • Editorial Board
    • Triological Society
    • Advertising Staff
    • Subscribe
  • Advertise
    • Place an Ad
    • Classifieds
    • Rate Card
  • Search

Laser, Radiotherapy Appear Similar in Oncologic Outcomes for Glottic Cancer

by Ed Susman • October 1, 2008

  • Tweet
  • Email
Print-Friendly Version

In the secondary endpoint of voice quality, we measured maximum phonation time, fundamental frequency, phonation intensity, and range, he said. Overall, the differences were not significant (p = 0.54). Stroboscopic analysis of mucosal waveform showed no statistical difference (p = 0.72); and the GRBAS (grade, roughness, breathiness, asthenia, strain) scale showed no statistical significance (p = 0.64). Subjective voice evaluation-normal versus mild versus severe dysphonia-showed no statistical significant differences (p = 0.64).

You Might Also Like

No related posts.

Explore This Issue
October 2008
Mark C. Weissler, MDWhat he showed is that these two treatment modalities are equivalent. I think most people believe that. It would also be reassuring to doctors who use these modalities.
-Mark C. Weissler, MD

We found trends favoring transoral laser surgery for improved local control, laryngectomy-free survival, and overall survival, but there was no significant difference in oncologic outcomes, Dr. Shah said. There was a trend favoring voice quality using external beam radiation.

Interpreting the Data

Mark C. Weissler, MD, the J.P. Riddle Distinguished Professor of Otolaryngology at the University of North Carolina- Chapel Hill, who moderated the session at which Dr. Shah delivered his paper, said, He tried to sort of make a case that surgical resection might be better, but it wasn’t supported by his data.

I think what he showed is that these two treatment modalities are equivalent. I think most people believe that. It would also be reassuring to doctors who use these modalities, said Dr. Weissler, who is also Chair of the UNC Clinical Cancer Advisory Committee and a clinical researcher at the Lineberger Comprehensive Cancer Center.

Dr. Shah acknowledged that his study was limited by few head-to-head comparisons, limited sample sizes, methodological issues of the studies, and poor correlation between objective and subjective measures.

There were no randomized clinical trial data, he said. The results were pooled analyses from retrospective studies. It was also limited by the duration of patient enrollment, as well as variability between studies regarding length of follow-up, tumor stage information, and staging criteria.

He said, however, that this study appears to be the first to compare the treatment modalities using meta-analytic techniques. We found oncologic control was most likely equivalent, and there was no clear difference in voice outcomes. Doctors should consider the potential morbidity of treatment and cost and utilization of health care resources and patient preference in considering which treatment would work best in each individual.

©2008 The Triological Society

Pages: 1 2 | Single Page

Filed Under: Departments, Head and Neck, Laryngology, Practice Focus, Tech Talk Tagged With: cancer, laryngectomy, laser, outcomes, research, surgery, technology, treatmentIssue: October 2008

You Might Also Like:

The Triological SocietyENTtoday is a publication of The Triological Society.

The Laryngoscope
Ensure you have all the latest research at your fingertips; Subscribe to The Laryngoscope today!

Laryngoscope Investigative Otolaryngology
Open access journal in otolaryngology – head and neck surgery is currently accepting submissions.

Classifieds

View the classified ads »

TRIO Best Practices

View the TRIO Best Practices »

Top Articles for Residents

  • Do Training Programs Give Otolaryngology Residents the Necessary Tools to Do Productive Research?
  • Why More MDs, Medical Residents Are Choosing to Pursue Additional Academic Degrees
  • What Physicians Need to Know about Investing Before Hiring a Financial Advisor
  • Tips to Help You Regain Your Sense of Self
  • Should USMLE Step 1 Change from Numeric Score to Pass/Fail?
  • Popular this Week
  • Most Popular
  • Most Recent
    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment
    • Complications for When Physicians Change a Maiden Name
    • Neurogenic Cough Is Often a Diagnosis of Exclusion
    • Vertigo in the Elderly: What Does It Mean?
    • Some Laryngopharyngeal Reflux Resists PPI Treatment
    • Vertigo in the Elderly: What Does It Mean?
    • New Developments in the Management of Eustachian Tube Dysfunction
    • Some Laryngopharyngeal Reflux Resists PPI Treatment
    • The Dramatic Rise in Tongue Tie and Lip Tie Treatment
    • Eustachian Tuboplasty: A Potential New Option for Chronic Tube Dysfunction and Patulous Disease
    • How To: A Modified Endoscopic Draf III Approach for Dermoid Cysts
    • How To: Inferior Meatus Augmentation Procedure for Empty Nose Syndrome
    • Otolaryngology Resident Says Art Helps Her Process Ideas on Wellness, Burnout
    • Age-Related Hearing Loss Is Associated with Incident Dementia in Adults Over 60
    • COVID-19 Associated with Upsurge in Otolaryngology Publications

Polls

Do you report near-miss or no-harm events to your patients?

View Results

Loading ... Loading ...
  • Polls Archive
  • Home
  • Contact Us
  • Advertise
  • Privacy Policy
  • Terms of Use

Visit: The Triological Society • The Laryngoscope • Laryngoscope Investigative Otolaryngology

Wiley
© 2022 The Triological Society. All Rights Reserved.
ISSN 1559-4939