Hearing loss genes vary widely in treatment favorability; thus, targeting development efforts to promising candidates will ensure the highest likelihood of clinical success. Several genes were identified as appealing targets.
Dietary Elements May Be Linked to a Lower Incidence of Tinnitus
Study results suggest a link between certain dietary elements and a lower incidence of tinnitus.
OCT Imaging Complements CT in Visualizing Normal and Pathological Ears
Although OCT was not capable of replacing CT due to its limited field of view (FOV) and inability to image through thick bony tissues, it visualized signs of pathology that are difficult to visualize with CT, suggesting its usefulness for some middle ear diagnostics.
Atmospheric Pressure Changes Linked to ELS Volume Changes in Patients with Unilateral Ménière’s Disease
Although OCT was not capable of replacing CT due to its limited field of view (FOV) and inability to image through thick bony tissues, it visualized signs of pathology that are difficult to visualize with CT, suggesting its usefulness for some middle ear diagnostics.
Excitement Around Gene Therapy for Hearing Restoration
Clinical trials focus on OTOF-associated hearing loss, but other genes identified as appealing next targets
Otolaryngology Applicants without Home Residency Programs Receive Fewer Interviews and Matches
What are the differences in otolaryngology interview and match outcomes between applicants with and without home residency programs?
MenQOL Assessment Instrument Yields Promising Initial Results
Subject to further study, the patient-reported outcome measure (PROM) MenQOL may be used to assess the effects of treatment on disease-specific quality of life in patients with MD
3D-Based Model Shown Most Effective in Segmenting Inner Ear for Calculation of EH Volume Ratio
The 3D U-Net model was shown to be superior in performance to the 2D model in analyzing EH volume ratio, and the 3D model with data pairing performed better than the model without data pairing.
Vestibular Disorders May Result in Impaired Cognitive Function
Findings indicate that vestibular disorders can result in impairments across various aspects of cognitive functioning, particularly in visuospatial cognition.
Systematic Review of AAV–Based Gene Therapy for Hereditary Deafness Presents Progress and Challenges
AAV-based gene therapy represents a promising therapeutic approach for hereditary deafness.
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