Current evidence indicates that the risk of meningitis and CNS infections after ESBS is low, especially in uncomplicated cases without CSF leaks. Post-operative antibiotics show no clear benefit in these patients and are not recommended. In cases with CSF leaks, the risk of infection is significantly higher, requiring careful management by the surgeon.
Despite limited randomized trials specific to AERD, the consistent improvements in sinonasal outcomes across studies strongly support dupilumab as an effective treatment for AERD patients post-FESS.
Chronic rhinosinusitis (CRS) is among the most prevalent chronic medical conditions globally. A survey of Canadian households reported the prevalence of CRS to be 5%. CRS is a clinical syndrome defined by persistent symptomatic inflammation of the mucosa in the nasal cavities and sinuses. A common subtype of CRS is CRS with nasal polyps (CRSwNP), which is identified through endoscopy or imaging
Epistaxis is a common emergency department (ED) presentation. Many cases are self-limited, but other cases may require an intervention to stop bleeding. Methods to manage epistaxis include nasal compression, topical vasoconstrictors, cautery, nasal packing, and even surgical ligation in severe cases.
ETI has been shown to have positive effects on multiple organ systems in cystic fibrosis patients.
The combination of lexacaftor/tezacaftor/ivacaftor has been shown to have positive effects on multiple organ systems.
Although the number of randomized control trials is lacking, the current literature suggests mucosal flap preservation may improve outcomes following endoscopic dacryocystorhinostomy.
Functional rhinoplasty is an umbrella term used to describe the various surgical techniques that alter the external nasal structure with the goal of improving nasal breathing. Numerous techniques have been described and shown to be successful.
There is enough evidence to support posterior nasal nerves (PNN) as an effective treatment for allergic rhinitis symptoms, particularly nasal congestion and rhinorrhea.
The best practice recommendation is not to routinely use prophylactic antibiotics with nasal packing, as antibiotic use does not appear to reduce complications and is not cost-effective.