Ogura lecturer draws on the experience of past leaders to move ahead in the treatment of oropharyngeal cancers
New Staging System Proposed for HPV-Related Oropharyngeal Cancer
Researchers propose a new staging system for human papillomavirus-related oropharyngeal cancers based on findings from the International Collaboration on Oropharyngeal cancer Network for Staging (ICON-S) study.
Optimizing Treatment for Oropharyngeal Cancer
The possibility of de-escalating treatment is being evaluated in a clinical trial of participants with HPV-positive stage III-IVA oropharyngeal cancer
Oral Rinse Samples of HPV DNA May Identify Recurrence Risk
For patients diagnosed with human papillomavirus (HPV)-related oropharyngeal cancer, detection of HPV DNA in oral rinse samples after diagnosis may provide a useful biomarker to identify patients at increased risk of recurrence after treatment
HPV Related to Rise in Head and Neck Cancers
Over the past 15 years, a distinct subgroup of head and neck cancers caused by the human papillomavirus (HPV) has emerged, particularly among white males between 45 and 54 years of age
Tests Emerging as Standards for Diagnosing HPV-Positive Oropharyngeal Cancer
Immunohistochemical analysis of p16 expression levels in tumor tissues, and it situ hybridization to detect many types of onocogenic HPV, are often used either alone, or in combination
SM12: Otolaryngologists Debate Resident Training, Implantable Hearing Aids, Oropharyngeal Cancer
Four pairs of experts squared off at the Triological Society Combined Sections Meeting in a session of mini-debates over limits on training of residents, treatment of Zenker’s diverticulum, implantable hearing aids and the best approach to oropharyngeal cancer.
Swallowing Function After TLM + Adjuvant Therapy
For patients with advanced-stage oropharyngeal cancer, how does transoral laser microsurgery (TLM) + adjuvant therapy impact swallowing function? Background: For survival reasons, patients with advanced oropharyngeal cancer have elected adjuvant therapy, which introduces treatment interventions known to acutely and chronically decrease swallowing ability. In recent years, minimally invasive surgical approaches, including transoral laser microsurgery (TLM), have […]
A Contemporary Review of Papillomavirus and Oropharynx Cancer
What is the evidence for the role of human papillomavirus (HPV) in the etiology of oropharyngeal cancers, methods of viral detection and the resulting clinical implications? Background: The incidence of head and neck squamous cell carcinoma (HNSCC) has remained stable over the last 15 years, while the incidence of oropharyngeal squamous cell carcinoma (OPSCC), linked both […]
HPV Status an Independent Prognostic Factor for Oropharyngeal Cancer Survival
What is the independent effect of human papillomavirus (HPV) on oropharyngeal cancer survival? Background: HPV has been associated with oropharyngeal cancer risk and appears to underlie the rising incidence of this disease in the U.S. and Europe. HPV-positive oropharyngeal cancers may be associated with a better prognosis than HPV-negative oropharyngeal cancers. Study design: Retrospective analysis of HPV […]