Despite limited randomized trials specific to AERD, the consistent improvements in sinonasal outcomes across studies strongly support dupilumab as an effective treatment for AERD patients post-FESS.

What Is Considered Adequate Surgery for Chronic Rhinosinusitis with Nasal Polyps?
Chronic rhinosinusitis (CRS) is among the most prevalent chronic medical conditions globally. A survey of Canadian households reported the prevalence of CRS to be 5%. CRS is a clinical syndrome defined by persistent symptomatic inflammation of the mucosa in the nasal cavities and sinuses. A common subtype of CRS is CRS with nasal polyps (CRSwNP), which is identified through endoscopy or imaging

Is Topical Tranexamic Acid Effective in Treating Epistaxis?
Epistaxis is a common emergency department (ED) presentation. Many cases are self-limited, but other cases may require an intervention to stop bleeding. Methods to manage epistaxis include nasal compression, topical vasoconstrictors, cautery, nasal packing, and even surgical ligation in severe cases.

Is Elexacaftor/Tezacaftor/Ivacaftor Effective in Treating Sinonasal Disease in Patients with Cystic Fibrosis?
ETI has been shown to have positive effects on multiple organ systems in cystic fibrosis patients.

Elexacaftor/tezacaftor/ivacaftor May be Effective in Treating Sinonasal Disease in Patients with Cystic Fibrosis
The combination of lexacaftor/tezacaftor/ivacaftor has been shown to have positive effects on multiple organ systems.

Using Mucosal Preservation Techniques in Endonasal Dacryocystorhinostomy Improves Long-Term Success
Although the number of randomized control trials is lacking, the current literature suggests mucosal flap preservation may improve outcomes following endoscopic dacryocystorhinostomy.

What Really Works in Functional Rhinoplasty?
Functional rhinoplasty is an umbrella term used to describe the various surgical techniques that alter the external nasal structure with the goal of improving nasal breathing. Numerous techniques have been described and shown to be successful.

Is Posterior Nasal Nerve Ablation Effective in Treating Symptoms of Allergic Rhinitis?
There is enough evidence to support posterior nasal nerves (PNN) as an effective treatment for allergic rhinitis symptoms, particularly nasal congestion and rhinorrhea.

When Is Antibiotic Prophylaxis for Nasal Packing Indicated?
The best practice recommendation is not to routinely use prophylactic antibiotics with nasal packing, as antibiotic use does not appear to reduce complications and is not cost-effective.

Is There a Role for Bedside Biopsy in the Evaluation of Acute Invasive Fungal Rhinosinusitis?
Is there a role for bedside biopsy in the evaluation of acute invasive fungal rhinosinusitis?
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