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Practice Focus » TRIO Best Practices » Rhinology

Does Dupilumab Improve Sinonasal Outcomes in AERD Patients?

April 8, 2026

Despite limited randomized trials specific to AERD, the consistent improvements in sinonasal outcomes across studies strongly support dupilumab as an effective treatment for AERD patients post-FESS.

What Is Considered Adequate Surgery for Chronic Rhinosinusitis with Nasal Polyps?

September 3, 2025

Chronic rhinosinusitis (CRS) is among the most prevalent chronic medical conditions globally. A survey of Canadian households reported the prevalence of CRS to be 5%. CRS is a clinical syndrome defined by persistent symptomatic inflammation of the mucosa in the nasal cavities and sinuses. A common subtype of CRS is CRS with nasal polyps (CRSwNP), which is identified through endoscopy or imaging

Is Topical Tranexamic Acid Effective in Treating Epistaxis?

April 3, 2025

Epistaxis is a common emergency department (ED) presentation. Many cases are self-limited, but other cases may require an intervention to stop bleeding. Methods to manage epistaxis include nasal compression, topical vasoconstrictors, cautery, nasal packing, and even surgical ligation in severe cases.

Is Elexacaftor/Tezacaftor/Ivacaftor Effective in Treating Sinonasal Disease in Patients with Cystic Fibrosis?

May 13, 2024

ETI has been shown to have positive effects on multiple organ systems in cystic fibrosis patients.

Elexacaftor/tezacaftor/ivacaftor May be Effective in Treating Sinonasal Disease in Patients with Cystic Fibrosis

October 3, 2023

The combination of lexacaftor/tezacaftor/ivacaftor has been shown to have positive effects on multiple organ systems.

Using Mucosal Preservation Techniques in Endonasal Dacryocystorhinostomy Improves Long-Term Success

July 18, 2023

Although the number of randomized control trials is lacking, the current literature suggests mucosal flap preservation may improve outcomes following endoscopic dacryocystorhinostomy.

What Really Works in Functional Rhinoplasty?

March 15, 2023

Functional rhinoplasty is an umbrella term used to describe the various surgical techniques that alter the external nasal structure with the goal of improving nasal breathing. Numerous techniques have been described and shown to be successful.

Is Posterior Nasal Nerve Ablation Effective in Treating Symptoms of Allergic Rhinitis?

September 30, 2022

There is enough evidence to support posterior nasal nerves (PNN) as an effective treatment for allergic rhinitis symptoms, particularly nasal congestion and rhinorrhea.

TRIO Best Practice

When Is Antibiotic Prophylaxis for Nasal Packing Indicated?

July 13, 2022

The best practice recommendation is not to routinely use prophylactic antibiotics with nasal packing, as antibiotic use does not appear to reduce complications and is not cost-effective.

Is There a Role for Bedside Biopsy in the Evaluation of Acute Invasive Fungal Rhinosinusitis?

February 16, 2022

Is there a role for bedside biopsy in the evaluation of acute invasive fungal rhinosinusitis?

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